Using this antibody with other myogenic markers such as muscle actin, desmin and vimentin is helpful for differentiation of tumor from muscle origin when used in a panel of antibodies. It is a useful marker for the identification for soft tissue tumors with muscle differentiation, i.e. leiomyomas and leiomyosarcomas. It is a useful marker for distinction of benign proliferative lesions of the breast from neoplastic proliferations.